Initial Empirical Antimicrobial Therapy: Duration and Subsequent Modifications

Recommended Initial Antimicrobial Therapy for Emphysematous Pyelonephritis

The aim of this study was to investigate the profiles of pathogens and patterns of antibiotic resistance of emphysematous pyelonephritis (EPN), offering recommendations for initial antibiotic treatment.Between January, 2001, and November, 2014, demographic data, presenting clinical features, management strategies, and treatment outcomes of 51 patients with EPN were retrospectively reviewed, ana...

Antimicrobial Modifications of Polymers

An initial Empirical Evaluation of the Influence of ERP Post-Implementation modifications on Business Process optimisation

In this research in progress paper, we present and discuss an initial empirical evaluation of a model on ERP post-implementation modifications. The theoretical foundation and derivation of a set of propositions from the model were reported recently (citation withheld); it categorises postimplementation modifications to ERP systems and relates it to business process optimisation. While ERP syste...

Initial Sulfonylurea Use and Subsequent Insulin Therapy in Older Subjects with Type 2 Diabetes Mellitus

BACKGROUND In type 2 diabetes mellitus (T2DM), progressive loss of beta cell function over time requires treatment intensification and eventually initiation of insulin for many patients. Relative to metformin, a greater rate of decline in beta cell function over time has been observed with sulfonylurea treatment. The present study examined the association between initial monotherapy with metfor...

Choice and Duration of Antimicrobial Therapy for Neonatal Sepsis and Meningitis

Neonatal sepsis is associated with increased mortality and morbidity including neurodevelopmental impairment and prolonged hospital stay. Signs and symptoms of sepsis are nonspecific, and empiric antimicrobial therapy is promptly initiated after obtaining appropriate cultures. However, many preterm and low birth weight infants who do not have infection receive antimicrobial agents during hospit...